Assuming the position that takes properties to be tropes rather than universals and takes ordinary objects as bundles of tropes, the essay first argues that the Law of the Identity of Indiscernibles survives the challenge raised by Black's "two-sphere universe". It is because the Law of Indiscernibles becomes a trivialconsequence of the assumed trope ontology. The essay then considers four construals of the thesis of Uniqueness differing in strength. The construals are developed in terms of both the possibility that tropes (...) of an object may be transferred to another object and the possibility that objects may survive cross-worldproperty changes. Finally, the essay argues that a trilemma arises from three intuitively innocent claims: (1) that same world objects do not share tropes, (2) that cross world objects may share some (but not all) tropes, and (3) that objects may survive cross-world property changes. And, unfortunately, Indiscernibles plays a role in giving rise to one horn of the trilemma. The essay suggests "ultraessentialism" as a possible way out of the trilemma. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

In January 2023, the Science and Security Board of the Bulletin of the Atomic Scientists moved the hands of the Doomsday Clock forward to 90 s before midnight.

I analyzed 298 open-ended responses of undergraduate students who have been reported for cheating to the question, “What, if anything, would have stopped you from committing your act of academic dishonesty?” These responses included a few major themes: students pled ignorance of what constitutes academic dishonesty and the consequences/seriousness associated with violations; students tended to deflect blame, usually by saying that their professor could have done something differently (neutralization); students did not feel they had enough time, resources, and/or skills to (...) get the desired result without taking responsibility for this lack of time, resources, and/or skills (strain); students felt they did not manage their time well with accepting the blame for the poor time management; and that a bad grade was not an option. These data and results are discussed in relation to the extant literature on the topic. (shrink)

In a strike to permit extra billing, physicians in Ontario, Canada, sought to balance their concerns for professional autonomy with their primary call to beneficence. But the right to reasonable compensation within a nationalized health care system is not on the same moral plane as the public's right to health care. Having failed to convince either the provincial government or the public of the soundness of their position, Ontario's doctors must now repair the damage done to the relationship with their (...) patients. (shrink)

Consider manipulation in which one agent, avoiding force, threat, or fraud mobilizes some non-concern motive of another so as to induce this other to behave or move differently than she would otherwise have behaved or moved, given her circumstances and her initial ranking of concerns. As an instance, imagine that I get us to miss the opening of a play that I have grudgingly agreed to attend by engaging your sublimated compulsive tendency to check the stove when we are halfway (...) to the theatre. Such motive manipulation is, I take it, widely regarded as morally worrisome. If it really is morally worrisome, then we should be able to explain adequately why it is so. But existing condemnations of manipulation come up short in this regard. In this paper, I develop and defend a more plausible account of the moral status of this phenomenon. (shrink)

The new Companion to Erasmus in the Renaissance Society of America's Texts and Studies Series draws on the insights of an international team of distinguished experts whose contributions are arrayed in eleven chapters followed by a detailed chronological catalogue of Erasmus' works and an up-to-date bibliography of secondary sources. The ambition of this companion is to illuminate every aspect of Erasmus' life, work, and legacy while providing an expert synthesis of the most inspiring research in the field. This volume will (...) be of invaluable assistance to students and teachers working in any of the numerous disciplines to which Erasmus devoted his tireless efforts, including philosophy, religion, history, rhetoric, education, and the history of the book. (shrink)

A critique of Rorty's own provocative political philosophy, as well as an in-depth look at both the issues concerning the relationship between the public and the private, and arguments on the role of reason in liberal political discourse generally.

The use of torture for interrogational purposes is frequently justified by a ‘ticking-bomb’ case, claiming that serious harms will come to a large group of people if a suspect is not tortured for the location of the bomb. In this paper, I will argue that an important recent defense of interrogational torture (Seumas Miller’s) faces several practical and epistemological problems. In this paper, I argue that these epistemological problems lead to the failure of Miller’s argument. I also argue that a (...) minimalist conception of epistemological duties gives us further reason to reject both Miller’s argument and torture more generally. I conclude that arguments for torture that are based on ticking-bomb cases are bound to face an irresolvable epistemological problem, closing one of the more prominent avenues used to justify torture. (shrink)

Central to Wilfrid Sellars ' philosophical system is his belief that science's current ontology is inadequate as it fails to provide for an acceptable account of perceptual experience. Unfortunately, this remains the most puzzling plank in his philosophy. Sellars himself argues for this position via his wellknown example of a pink ice cube and its homogeneous colour. This homogeneity, says Sellars, bars the acceptance of science's present ontology of achromatic particles, and requires the introduction of items which are truly coloured. (...) Only with such a revised and expanded ontology, with all that entails, can science adequately meet its explanatory demands. I aim here to remedy at least some of the confusions and misunderstandings this position has engendered. But I mean to take a different route from Sellars. In short, given the problems with Sellars ' views on homogeneity, I will argue for the Sellarsian conclusion as to the inadequacy of present scientific ontologies, yet without reliance on the puzzling doctrine of homogeneity. I begin then with a detailed examination of Sellars official position, indicate the trouble spots, and begin an alternative route. As I conceive things, however, the position I will sketch is still thoroughly Sellarsian, for it proceeds from premises Sellars himself has endorsed. (shrink)

This paper examines Charles Peirce's graphical notation for first-order logic with identity. The notation forms a part of his system of "existential graphs," which Peirce considered to be his best work in logic. In this paper a Tarskian semantics is provided for the graphical system.

Recently a gender-selective harvesting strategy has been proposed for possible control of aquatic invasive species, wherein females of the invasive species are harvested, whilst stocking the males (abbreviated as FHMS strategy) (Lyu et al. in Nat Resour Model 33(2):e12252, 2020). We consider the FHMS strategy with a weak Allee effect, and show that its extinction boundary need not be hyperbolic. To the best of our knowledge, this is the first example of a non-hyperbolic extinction boundary in two-compartment mating models structured (...) by sex. The model possesses a rich dynamical structure, with several local co-dimension one bifurcations occurring. We also show the occurrence of a global homoclinic bifurcation, which has applicability for large scale strategic bio-control. (shrink)

Contrary to Vaesen's argument that humans are unique with respect to nine cognitive capacities essential for tool use, we suggest that although such cognitive processes contribute to variation in tool use, it does not follow that these capacities arenecessaryfor tool use, nor that tool use shaped cognition per se, given the available data in cognitive neuroscience and behavioral biology.

The Moral Foundations of Trust seeks to explain why people place their faith in strangers, and why doing so matters. Trust is a moral value that does not depend upon personal experience or on interacting with people in civic groups or informal socializing. Instead, we learn to trust from our parents, and trust is stable over long periods of time. Trust depends on an optimistic world view: the world is a good place and we can make it better. Trusting people (...) are more likely to give through charity and volunteering. Trusting societies are more likely to redistribute resources from the rich to the poor. Trust has been in decline in the United States for over 30 years. The roots of this decline are traceable to declining optimism and increasing economic inequality, which Uslaner supports by aggregate time series in the United States and cross-sectional data across market economies. (shrink)

Philosophy has long struggled to understand the nature of color. The central role color plays in our lives, in visual experience, in art, as a metaphor for emotions, has made it an obvious candidate for philosophical reflection. Understanding the nature of color, however, has proved a daunting task, despite the numerous fields that contribute to the project. Even knowing how to start can be difficult. Is color to be understood as an objective part of reality, a property of objects with (...) a status similar to shape and size? Or is color more like pain, to be found only in experience and so somehow subjective? Or is color more like what some have said about time--that it seems real until we reflect enough, where we come ultimately to dismiss it as mere illusion? If color is more like shape and size, can we give a scientific account of it? Various strategies exist for this option--taking the color of an object to be just a complicated texture of that object, one that reflects certain wavelengths. Or perhaps color is merely a disposition to cause experiences in us, as salt has a disposition to dissolve. On the other hand, if color is more like pain, and found only in subjective experience, what is the nature of color experience? How, for instance, does an experience of red differ from an experience of blue, or from an experience of pain for that matter? Finally, if color is mere illusion, how do we continue to be so taken in by that illusion and how can something unreal seem so real and important to us? (shrink)

Several accounts of logical truth are compared and shown to define distinct concepts. Nevertheless, conditions are given under which they happen to declare exactly the same sentences logically true. These conditions involve the variety of objects in the domain, the richness of the language, and the logical resources available. It is argued that the class of sentences declared logically true by each of the accounts depends on particularities of the actual world.

This paper explores how image worship was conceptualized and represented by Chinese authors during the first four centuries of Buddhist presence in China. Previous scholarship has argued that image worship was initially seen in China as a distinctively Buddhist practice, so much so that Buddhism was even known to the Chinese as the “Religion of Images”. By examining the history of the interpretation of this term, the evolution of stories about sacred images, and the presentation of image worship in debates (...) about the compatibility of Buddhism with Chinese culture, I will argue that image worship was first seen as a distinctly Buddhist or non-Chinese practice only in the late fifth century. Ironically, image worship came to be seen or represented as “foreign” only long after it had already become part of most forms of Chinese religion. (shrink)

Academic dishonesty occurs at alarming rates in higher education. In the present study, we examined predictors of academic cheating behaviors, and beliefs in the acceptability of cheating, in disliked courses at two large universities, using structural equation modeling. Perceived mastery and extrinsic goal structures were related to beliefs about cheating but not cheating behaviors. Beliefs in the acceptability of cheating were more likely to be endorsed in math and science courses. College students were more likely to cheat and to believe (...) in the acceptability of cheating when they reported a high need for sensation. (shrink)

There are entitlements, opportunities, and rights presently reserved to married couples by the basic structure of society, its major social institutions. Some claim that this is as it should be. But given the abiding effects of the basic structure on the prospects of individuals living within it, restrictions on liberty built into the basic structure require justification. One might think that we could justify reserving the benefits of marriage to married couples by appealing to harm prevention. In this paper, I (...) argue that the prospects of doing so successfully are dim. (shrink)

Recently, the US has joined many European jurisdictions in extending civil marriage to same sex as well as different sex dyads. Many liberals regard this as a development worth entrenching. But a prominent recent liberal challenge to civil marriage claims otherwise. According to this challenge, by defining and conferring civil marriage, the state privileges some relationships over others that serve equally well the important liberal goal of fostering effective liberal citizenship, in violation of a prominent interpretation of the doctrine of (...) state neutrality. Theorists who press this challenge, such as Elizabeth Brake and Tamara Metz, argue that it can be met effectively only by dismantling civil marriage and replacing it with more inclusive state-maintained arrangements. So far, prominent responses to this neutralist challenge to civil marriage have focused on the special value of either the relationships to which civil marriage currently extends, or the special value of civil marriage itself. In this article, I develop an alternative reply to this neutralist challenge to civil marriage, one focusing instead on the special vulnerabilities of some of the liberally valuable relationships to which civil marriage currently extends, amorous caregiving dyads. (shrink)

Most people do not know there are different kinds of medical studies; some are conducted on people who already have a disease or medical condition, and others are performed on healthy volunteers who want to help science find answers. No matter what sort of research you are invited to participate in, or whether you are a patient when you are asked, it’s entirely up to you whether or not to do it. This decision is important and may have many implications (...) for your health and well-being, as well as those of other patients now and in the future. Making a good decision – the right one for you – requires you to become educated about topics you may not have thought about before, some of which may be quite complicated. This chapter explains the key issues to help you make a good decision. (shrink)

Let the marriage bond be the set of extralegal obligations to one another that individuals acquire in getting married. And let a conception of the marriage bond be an account of the nature and content of these. Here, I argue that the conception of this bond dominant among us is uncongenial to romantic love among individuals of a certain psychological type. Then, after articulating a conception more congenial to romantic love among such individuals, I argue that if we wish to (...) make marriage safer for love, we should make room in our thinking and practice for this conception, embracing a form of marital pluralism. (shrink)

Objective: There are benefits and risks of giving patients more granular control of their personal health information in electronic health record (EHR) systems. When designing EHR systems and policies, informaticists and system developers must balance these benefits and risks. Ethical considerations should be an explicit part of this balancing. Our objective was to develop a structured ethics framework to accomplish this. -/- Methods: We reviewed existing literature on the ethical and policy issues, developed an ethics framework called a “Points to (...) Consider” (P2C) document, and convened a national expert panel to review and critique the P2C. -/- Results: We developed the P2C to aid informaticists designing an advanced query tool for an electronic health record (EHR) system in Indianapolis. The P2C consists of six questions (“Points”) that frame important ethical issues, apply accepted principles of bioethics and Fair Information Practices, comment on how questions might be answered, and address implications for patient care. -/- Discussion: The P2C is intended to clarify whatis at stake when designers try to accommodate potentially competing ethical commitments and logistical realities. The P2C was developed to guide informaticists who were designing a query tool in an existing EHR that would permit patient granular control. While consideration of ethical issues is coming to the forefront of medical informatics design and development practices, more reflection is needed to facilitate optimal collaboration between designers and ethicists. This report contributes to that discussion. (shrink)

Ethics should guide the design of electronic health records (EHR), and recognized principles of bioethics can play an important role. This approach was adopted recently by a team of informaticists designing and testing a system where patients exert granular control over who views their personal health information. While this method of building ethics in from the start of the design process has significant benefits, questions remain about how useful the application of bioethics principles can be in this process, especially when (...) principles conflict. For instance, while the ethical principle of respect for autonomy supports a robust system of granular control, the principles of beneficence and non-maleficence counsel restraint due to the danger of patients being harmed by restrictions on provider access to data. Conflict between principles has long been recognized by ethicists and has even motivated attacks on approaches that state and apply principles. In this paper we show how using ethical principles can help in the design of EHRs by first, explaining how ethical principles can and should be used generally, and then by, discuss how attention to details in specific cases can show that the tension between principles is not as bad as it initially appeared. We conclude by suggesting further ways in which the application of these (and other) principles can add value to the ongoing discussion of patient involvement in their health care. This is a new approach to linking principles to informatics design that we expect will stimulate further interest. (shrink)