Assuming the position that takes properties to be tropes rather than universals and takes ordinary objects as bundles of tropes, the essay first argues that the Law of the Identity of Indiscernibles survives the challenge raised by Black's "two-sphere universe". It is because the Law of Indiscernibles becomes a trivialconsequence of the assumed trope ontology. The essay then considers four construals of the thesis of Uniqueness differing in strength. The construals are developed in terms of both the possibility that tropes (...) of an object may be transferred to another object and the possibility that objects may survive cross-worldproperty changes. Finally, the essay argues that a trilemma arises from three intuitively innocent claims: (1) that same world objects do not share tropes, (2) that cross world objects may share some (but not all) tropes, and (3) that objects may survive cross-world property changes. And, unfortunately, Indiscernibles plays a role in giving rise to one horn of the trilemma. The essay suggests "ultraessentialism" as a possible way out of the trilemma. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

In January 2023, the Science and Security Board of the Bulletin of the Atomic Scientists moved the hands of the Doomsday Clock forward to 90 s before midnight.

I analyzed 298 open-ended responses of undergraduate students who have been reported for cheating to the question, “What, if anything, would have stopped you from committing your act of academic dishonesty?” These responses included a few major themes: students pled ignorance of what constitutes academic dishonesty and the consequences/seriousness associated with violations; students tended to deflect blame, usually by saying that their professor could have done something differently (neutralization); students did not feel they had enough time, resources, and/or skills to (...) get the desired result without taking responsibility for this lack of time, resources, and/or skills (strain); students felt they did not manage their time well with accepting the blame for the poor time management; and that a bad grade was not an option. These data and results are discussed in relation to the extant literature on the topic. (shrink)

In a strike to permit extra billing, physicians in Ontario, Canada, sought to balance their concerns for professional autonomy with their primary call to beneficence. But the right to reasonable compensation within a nationalized health care system is not on the same moral plane as the public's right to health care. Having failed to convince either the provincial government or the public of the soundness of their position, Ontario's doctors must now repair the damage done to the relationship with their (...) patients. (shrink)

A critique of Rorty's own provocative political philosophy, as well as an in-depth look at both the issues concerning the relationship between the public and the private, and arguments on the role of reason in liberal political discourse generally.

The use of torture for interrogational purposes is frequently justified by a ‘ticking-bomb’ case, claiming that serious harms will come to a large group of people if a suspect is not tortured for the location of the bomb. In this paper, I will argue that an important recent defense of interrogational torture (Seumas Miller’s) faces several practical and epistemological problems. In this paper, I argue that these epistemological problems lead to the failure of Miller’s argument. I also argue that a (...) minimalist conception of epistemological duties gives us further reason to reject both Miller’s argument and torture more generally. I conclude that arguments for torture that are based on ticking-bomb cases are bound to face an irresolvable epistemological problem, closing one of the more prominent avenues used to justify torture. (shrink)

Recently a gender-selective harvesting strategy has been proposed for possible control of aquatic invasive species, wherein females of the invasive species are harvested, whilst stocking the males (abbreviated as FHMS strategy) (Lyu et al. in Nat Resour Model 33(2):e12252, 2020). We consider the FHMS strategy with a weak Allee effect, and show that its extinction boundary need not be hyperbolic. To the best of our knowledge, this is the first example of a non-hyperbolic extinction boundary in two-compartment mating models structured (...) by sex. The model possesses a rich dynamical structure, with several local co-dimension one bifurcations occurring. We also show the occurrence of a global homoclinic bifurcation, which has applicability for large scale strategic bio-control. (shrink)

Contrary to Vaesen's argument that humans are unique with respect to nine cognitive capacities essential for tool use, we suggest that although such cognitive processes contribute to variation in tool use, it does not follow that these capacities arenecessaryfor tool use, nor that tool use shaped cognition per se, given the available data in cognitive neuroscience and behavioral biology.

The new Companion to Erasmus in the Renaissance Society of America's Texts and Studies Series draws on the insights of an international team of distinguished experts whose contributions are arrayed in eleven chapters followed by a detailed chronological catalogue of Erasmus' works and an up-to-date bibliography of secondary sources. The ambition of this companion is to illuminate every aspect of Erasmus' life, work, and legacy while providing an expert synthesis of the most inspiring research in the field. This volume will (...) be of invaluable assistance to students and teachers working in any of the numerous disciplines to which Erasmus devoted his tireless efforts, including philosophy, religion, history, rhetoric, education, and the history of the book. (shrink)

The Moral Foundations of Trust seeks to explain why people place their faith in strangers, and why doing so matters. Trust is a moral value that does not depend upon personal experience or on interacting with people in civic groups or informal socializing. Instead, we learn to trust from our parents, and trust is stable over long periods of time. Trust depends on an optimistic world view: the world is a good place and we can make it better. Trusting people (...) are more likely to give through charity and volunteering. Trusting societies are more likely to redistribute resources from the rich to the poor. Trust has been in decline in the United States for over 30 years. The roots of this decline are traceable to declining optimism and increasing economic inequality, which Uslaner supports by aggregate time series in the United States and cross-sectional data across market economies. (shrink)

Academic dishonesty occurs at alarming rates in higher education. In the present study, we examined predictors of academic cheating behaviors, and beliefs in the acceptability of cheating, in disliked courses at two large universities, using structural equation modeling. Perceived mastery and extrinsic goal structures were related to beliefs about cheating but not cheating behaviors. Beliefs in the acceptability of cheating were more likely to be endorsed in math and science courses. College students were more likely to cheat and to believe (...) in the acceptability of cheating when they reported a high need for sensation. (shrink)

This paper explores how image worship was conceptualized and represented by Chinese authors during the first four centuries of Buddhist presence in China. Previous scholarship has argued that image worship was initially seen in China as a distinctively Buddhist practice, so much so that Buddhism was even known to the Chinese as the “Religion of Images”. By examining the history of the interpretation of this term, the evolution of stories about sacred images, and the presentation of image worship in debates (...) about the compatibility of Buddhism with Chinese culture, I will argue that image worship was first seen as a distinctly Buddhist or non-Chinese practice only in the late fifth century. Ironically, image worship came to be seen or represented as “foreign” only long after it had already become part of most forms of Chinese religion. (shrink)

Several accounts of logical truth are compared and shown to define distinct concepts. Nevertheless, conditions are given under which they happen to declare exactly the same sentences logically true. These conditions involve the variety of objects in the domain, the richness of the language, and the logical resources available. It is argued that the class of sentences declared logically true by each of the accounts depends on particularities of the actual world.

There are entitlements, opportunities, and rights presently reserved to married couples by the basic structure of society, its major social institutions. Some claim that this is as it should be. But given the abiding effects of the basic structure on the prospects of individuals living within it, restrictions on liberty built into the basic structure require justification. One might think that we could justify reserving the benefits of marriage to married couples by appealing to harm prevention. In this paper, I (...) argue that the prospects of doing so successfully are dim. (shrink)

Recently, the US has joined many European jurisdictions in extending civil marriage to same sex as well as different sex dyads. Many liberals regard this as a development worth entrenching. But a prominent recent liberal challenge to civil marriage claims otherwise. According to this challenge, by defining and conferring civil marriage, the state privileges some relationships over others that serve equally well the important liberal goal of fostering effective liberal citizenship, in violation of a prominent interpretation of the doctrine of (...) state neutrality. Theorists who press this challenge, such as Elizabeth Brake and Tamara Metz, argue that it can be met effectively only by dismantling civil marriage and replacing it with more inclusive state-maintained arrangements. So far, prominent responses to this neutralist challenge to civil marriage have focused on the special value of either the relationships to which civil marriage currently extends, or the special value of civil marriage itself. In this article, I develop an alternative reply to this neutralist challenge to civil marriage, one focusing instead on the special vulnerabilities of some of the liberally valuable relationships to which civil marriage currently extends, amorous caregiving dyads. (shrink)

Most people do not know there are different kinds of medical studies; some are conducted on people who already have a disease or medical condition, and others are performed on healthy volunteers who want to help science find answers. No matter what sort of research you are invited to participate in, or whether you are a patient when you are asked, it’s entirely up to you whether or not to do it. This decision is important and may have many implications (...) for your health and well-being, as well as those of other patients now and in the future. Making a good decision – the right one for you – requires you to become educated about topics you may not have thought about before, some of which may be quite complicated. This chapter explains the key issues to help you make a good decision. (shrink)

Let the marriage bond be the set of extralegal obligations to one another that individuals acquire in getting married. And let a conception of the marriage bond be an account of the nature and content of these. Here, I argue that the conception of this bond dominant among us is uncongenial to romantic love among individuals of a certain psychological type. Then, after articulating a conception more congenial to romantic love among such individuals, I argue that if we wish to (...) make marriage safer for love, we should make room in our thinking and practice for this conception, embracing a form of marital pluralism. (shrink)

RésuméUne «situation de choix paradoxal» est une situation dans laquelle un agent connaîtrait davantage de succès en regard des préférences qu'il a effectivement, si ces préférences étaient différentes de ce qu'elles sont. Supposons que les agents rationnels ne choisissent pas à l'encontre de leurs préférences, que leur choix n'est déterminé que par ces préférences, et que leurs préférences intrinsèques ne changent pas de façon spontanée, automatique et directe sous l'influence de la critique rationnelle. Même dans de telles hypothèses, les agents (...) rationnels peuvent résoudre optimalement un éventail de situations de choix paradoxal au moyen de mécanismes qui les amènent à réviser leurs préférences. Dans cet article, je présente et défends un tel modèle de révision rationnelle des préférences. (shrink)

Consider manipulation in which one agent, avoiding force, threat, or fraud mobilizes some non-concern motive of another so as to induce this other to behave or move differently than she would otherwise have behaved or moved, given her circumstances and her initial ranking of concerns. As an instance, imagine that I get us to miss the opening of a play that I have grudgingly agreed to attend by engaging your sublimated compulsive tendency to check the stove when we are halfway (...) to the theatre. Such motive manipulation is, I take it, widely regarded as morally worrisome. If it really is morally worrisome, then we should be able to explain adequately why it is so. But existing condemnations of manipulation come up short in this regard. In this paper, I develop and defend a more plausible account of the moral status of this phenomenon. (shrink)